Intranasal fentanyl versus placebo for pain in children during catheterization for voiding cystourethrography
Autor: | Ruth P. Lim, Seen Chung, Ran D. Goldman |
---|---|
Rok vydání: | 2009 |
Předmět: |
Male
medicine.medical_specialty Voiding cystourethrogram Pain Urination Placebo law.invention Fentanyl Randomized controlled trial Double-Blind Method law Medicine Humans Radiology Nuclear Medicine and imaging Adverse effect Child Administration Intranasal Neuroradiology Pain Measurement medicine.diagnostic_test business.industry Urography Placebo Effect Surgery Analgesics Opioid Distress Treatment Outcome Anesthesia Child Preschool Pediatrics Perinatology and Child Health Nasal administration Female business Urinary Catheterization medicine.drug |
Zdroj: | Pediatric radiology. 40(7) |
ISSN: | 1432-1998 |
Popis: | Voiding cystourethrogram (VCUG) is a common procedure at pediatric tertiary care centres that can be painful as it involves a urinary catheter. Currently there are no widely utilized protocols for non-topical medications to decrease pain that children feel during catheterization. To determine if intranasal (IN) fentanyl is effective at decreasing pain that children feel during catheterization of VCUG when compared with sterile water. We performed a double-blind randomized controlled trial, using IN fentanyl (2 μg/kg) compared to placebo (sterile water,) in children 4–8 years of age scheduled for elective VCUG in one urban pediatric tertiary center. Using the Face Pain Score-Revised, children receiving IN fentanyl scored 2.58 (1.93–3.25 95% CI) while those receiving sterile water scored 2.86 (2.20–3.51 95% CI) showing no statistically significant difference. There were no adverse events. Although we were unable to show a statistically significant difference between our study and control groups, we believe that this may be due to technique (positioning, delivery device) and timing of administration of IN fentanyl as well as multi-factorial causes of distress during VCUG. Future studies investigating alternative delivery techniques of IN fentanyl for analgesia during VCUG may yield more promising results. |
Databáze: | OpenAIRE |
Externí odkaz: |