Clinical and Histological Characteristics of Papillary Thyroid Microcarcinoma: Results of a Retrospective Study in 243 Patients
| Autor: | Ettore C. degli Uberti, Fiorenza Bertelli, Lewis E. Braverman, Roberta Elisa Rossi, Elio Roti, Elizabeth N. Pearce, L. Busutti, Maria Rosaria Ambrosio, Giorgio Trasforini |
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| Rok vydání: | 2006 |
| Předmět: |
medicine.medical_specialty
Endocrinology Diabetes and Metabolism Clinical Biochemistry Population Papillary Thyroid Microcarcinoma Biochemistry Iodine Radioisotopes Thyroid carcinoma Endocrinology Internal medicine Biopsy medicine Humans Thyroid Neoplasms education Retrospective Studies education.field_of_study Tumor size medicine.diagnostic_test business.industry Biopsy Needle Biochemistry (medical) Thyroid Cancer Retrospective cohort study medicine.disease Carcinoma Papillary Surgery medicine.anatomical_structure Lymphatic Metastasis Thyroidectomy business |
| Zdroj: | The Journal of Clinical Endocrinology & Metabolism. 91:2171-2178 |
| ISSN: | 1945-7197 0021-972X |
| Popis: | The recognition of thyroid microcarcinoma has increased due to the widespread use of ultrasound-guided fine-needle aspiration biopsies.The objective of this study was to describe histological and clinical characteristics of papillary thyroid microcarcinoma (PTMC) less than or equal to 1 cm.This study was a retrospective cohort.This study was conducted at a university hospital endocrine clinic.Over a 9-yr period, 243 consecutive patients with PTMC were studied.PTMC was an incidental finding at surgery in 21.4% of the PTMC cases. There were no differences in the clinical characteristics between those with incidental PTMC and those with suspected thyroid carcinoma. None of the patients with a cancer less than 8 mm had distant metastases, whereas distant metastases were observed in patients with cancers/= 8 mm (P/= 0.05). Disease-related mortality was not observed.PTMC is prevalent in the population. Among patients with PTMC, tumor size more than 8 mm is associated with more aggressive disease. |
| Databáze: | OpenAIRE |
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