Clinical and Angiographic Outcomes with the Combined Local Aspiration and Retriever in the North American Solitaire Stent-Retriever Acute Stroke (NASA) Registry
Autor: | Franklin A. Marden, Ansaar T Rai, Aamir Badruddin, Joey English, Andrew R. Xavier, Gavin W. Britz, Albert J Yoo, Guilherme Dabus, Coleman O. Martin, Hormozd Bozorgchami, Nils Mueller-Kronast, Alicia C. Castonguay, Osama O. Zaidat, Michael G. Abraham, Italo Linfante, Thanh N. Nguyen, Ashish Nanda, Ritesh Kaushal, Rishi Gupta, M. Asif Taqi, Vallabh Janardhan, Hashem Shaltoni, Chung-Huan J Sun, Peng R Chen, William E. Holloway, Alex Abou-Chebl, Michael T. Froehler, R Novakovic, Raul G Nogueira, Tim W. Malisch |
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Rok vydání: | 2018 |
Předmět: |
medicine.medical_specialty
Solitaire Cryptographic Algorithm Original Paper business.industry Cerebral infarction medicine.medical_treatment Atrial fibrillation Thrombolysis 030204 cardiovascular system & hematology medicine.disease Surgery 03 medical and health sciences Catheter 0302 clinical medicine medicine Neurology (clinical) Cardiology and Cardiovascular Medicine business Stroke Solitaire stent 030217 neurology & neurosurgery Acute stroke |
Zdroj: | Interventional neurology. 7(1-2) |
ISSN: | 1664-9737 |
Popis: | Background: Various techniques are used to enhance the results of mechanical thrombectomy with stent-retrievers, including proximal arrest with balloon guide catheter (BGC), conventional large bore proximal catheter (CGC), or in combination with local aspiration through a large-bore catheter positioned at the clot interface (Aspiration-Retriever Technique for Stroke [ARTS]). We evaluated the impact of ARTS in the North American Solitaire Acute Stroke (NASA) registry. Summary: Data on the use of the aspiration technique were available for 285 anterior circulation patients, of which 29 underwent ARTS technique, 131 CGC, and 125 BGC. Baseline demographics were comparable, except that ARTS patients are less likely to have hypertension or atrial fibrillation. The ARTS group had more ICA occlusions (41.4 vs. 22% in the BGC, p = 0.04 and 26% in CGC, p = 0.1) and less MCA/M1 occlusions (44.8 vs. 68% in BGC and 62% in CGC). Time from arterial puncture to reperfusion or end of procedure with ARTS was shorter than with CGC (54 vs. 91 min, p = 0.001) and was comparable to the BGC time (54 vs. 67, p = 0.11). Final degree of reperfusion was comparable among the groups (TICI [modified Thrombolysis in Cerebral Infarction] score 2b or higher was 72 vs. 70% for CGC vs. 78% for BGC). Procedural complications, mortality, and good clinical outcome at 90 days were similar between the groups. Key Messages: The ARTS mechanical thrombectomy in acute ischemic stroke patients appears to yield better results as compared to the use of CGCs with no significant difference when compared to BGC. This early ARTS technique NASA registry data are limited by the earlier generation distal large bore catheters and small sample size. Future studies should focus on the comparison of ARTS and BGC techniques. |
Databáze: | OpenAIRE |
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