Effect of personalized nutrition on health-related behaviour change: evidence from the Food4Me European randomized controlled trial
| Autor: | Rosalind Fallaize, Christina Mavrogianni, Cyril F. M. Marsaux, Eileen R. Gibney, Anna L. Macready, Agnieszka Surwiłło, Magdalena Godlewska, Christina P. Lambrinou, Keith A. Grimaldi, Marianne C. Walsh, Yannis Manios, John C. Mathers, Lydia Tsirigoti, Carlos Celis-Morales, Julie A. Lovegrove, Lorraine Brennan, Jacqueline Hallmann, Santiago Navas-Carretero, Hannelore Daniel, Hannah Forster, Clare B. O’Donovan, Ben van Ommen, Laurence D. Parnell, Iwona Traczyk, J. Alfredo Martínez, Michael J. Gibney, Jildau Bouwman, Silvia Kolossa, Katherine M. Livingstone, Clara Woolhead, Rodrigo San-Cristobal, George Moschonis, Christian A. Drevon, John N. S. Matthews, Wim H. M. Saris |
|---|---|
| Přispěvatelé: | Promovendi NTM, RS: NUTRIM - HB/BW section A, RS: NUTRIM - R1 - Obesity, diabetes and cardiovascular health, RS: NUTRIM - R1 - Metabolic Syndrome |
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Gerontology Male obesity Epidemiology Health Behavior Alternative medicine law.invention Body Mass Index 0302 clinical medicine Randomized controlled trial law Precision Medicine Health Education INDEX 2. Zero hunger Personalized nutrition General Medicine Middle Aged 16. Peace & justice WEB 3. Good health Europe Phenotype NONCOMMUNICABLE DISEASES Health education Female Adult medicine.medical_specialty internet-based Behaviour change Adolescent Genotype QUESTIONNAIRE 030209 endocrinology & metabolism 03 medical and health sciences Young Adult medicine Humans Exercise Life Style Aged metabolic health Internet 030109 nutrition & dietetics business.industry Nutritional Requirements Health related Genetic Variation Precision medicine Diet randomized controlled trial business RESPONSES |
| Zdroj: | International Journal of Epidemiology, 46(2), 578-588. Oxford University Press |
| ISSN: | 1464-3685 0300-5771 |
| Popis: | Background: Optimal nutritional choices are linked with better health, but many current interventions to improve diet have limited effect. We tested the hypothesis that providing personalized nutrition (PN) advice based on information on individual diet and lifestyle, phenotype and/or genotype would promote larger, more appropriate, and sustained changes in dietary behaviour.\ud \ud Methods: Adults from seven European countries were recruited to an internet-delivered intervention (Food4Me) and randomized to: (i) conventional dietary advice (control) or to PN advice based on: (ii) individual baseline diet; (iii) individual baseline diet plus phenotype (anthropometry and blood biomarkers); or (iv) individual baseline diet plus phenotype plus genotype (five diet-responsive genetic variants). Outcomes were dietary intake, anthropometry and blood biomarkers measured at baseline and after 3 and 6 months’ intervention.\ud \ud Results: At baseline, mean age of participants was 39.8 years (range 18–79), 59% of participants were female and mean body mass index (BMI) was 25.5 kg/m2. From the enrolled participants, 1269 completed the study. Following a 6-month intervention, participants randomized to PN consumed less red meat [-5.48 g, (95% confidence interval:-10.8,-0.09), P = 0.046], salt [-0.65 g, (−1.1,-0.25), P = 0.002] and saturated fat [-1.14 % of energy, (−1.6,-0.67), P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|