A peer-education intervention to reduce injection risk behaviors for HIV and hepatitis C virus infection in young injection drug users
| Autor: | Steffanie A. Strathdee, Alan E. Greenberg, Elizabeth T. Golub, Sharon M. Hudson, Lawrence J. Ouellet, Holly Hagan, Richard S. Garfein, Mary H. Latka, Farzana Kapadia, David W. Purcell, Debra L. Hanson, Hanne Thiede |
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| Rok vydání: | 2007 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Sexual Behavior Hepatitis C virus Immunology HIV Infections medicine.disease_cause Peer Group law.invention Acquired immunodeficiency syndrome (AIDS) Randomized controlled trial Behavior Therapy law Internal medicine Humans Immunology and Allergy Medicine Risk factor Young adult Substance Abuse Intravenous Health Education business.industry Incidence virus diseases Peer group Hepatitis C medicine.disease United States Treatment Outcome Infectious Diseases Adolescent Behavior Female business Risk Reduction Behavior Peer education |
| Zdroj: | AIDS. 21:1923-1932 |
| ISSN: | 0269-9370 |
| Popis: | To evaluate whether a behavioral intervention, which taught peer education skills, could reduce injection and sexual risk behaviors associated with primary HIV and hepatitis C virus infection (HCV) among young injection drug users (IDU).We conducted a randomized controlled trial involving HIV and HCV antibody-negative IDU, aged 15-30 years, recruited in five United States cities. A six-session, small-group, cognitive behavioral, skills-building intervention in which participants were taught peer education skills (n = 431) was compared with a time-equivalent attention control (n = 423). Baseline visits included interviews for sociodemographic, psychosocial, and behavioral factors during the previous 3 months; HIV and HCV antibody testing; and pre/posttest counselling. Procedures were repeated 3 and 6 months postintervention.The intervention produced a 29% greater decline in overall injection risk 6 months postintervention relative to the control [proportional odds ratio 0.71; 95% confidence limit (CL) 0.52, 0.97], and a 76% decrease compared with baseline. Decreases were also observed for sexual risk behaviors, but they did not differ by trial arm. Overall HCV infection incidence (18.4/100 person-years) did not differ significantly across trial arms (relative risk 1.15; 95% CL 0.72, 1.82). No HIV seroconversions were observed.Interventions providing information, enhancing risk-reduction skills, and motivating behavior change through peer education training can reduce injection risk behaviors, although risk elimination might be necessary to prevent HCV transmission. |
| Databáze: | OpenAIRE |
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