Manifestaciones cutáneas de amiloidosis sistémica como clave diagnóstica: Caso clínico

Autor:	Marco Chahuán Y, Mª Magdalena Farías N, Sergio González B, Gabriela Araya C, Álvaro Abarzúa A, Félix Fich S, Consuelo Cárdenas D
Rok vydání:	2012
Předmět:	Amyloid Pathology medicine.medical_specialty medicine.diagnostic_test business.industry Amyloidosis Dystrophy Physical examination General Medicine medicine.disease Malaise Skin diseases body regions AA amyloidosis Biopsy medicine Macroglossia sense organs medicine.symptom business Rare disease
Zdroj:	Revista médica de Chile v.140 n.4 2012 SciELO Chile CONICYT Chile instacron:CONICYT
ISSN:	0034-9887
Popis:	Background: Systemic amyloidosis is a rare disease that can affect any organ. Its clinical manifestations are varied and nonspecific. The skin involvement of this disease is common and can be easily recognized on physical examination. We report a 57-year-old male presenting with a two years history of malaise, dyspnea and myalgias. On physical examination, ungueal dystrophy, orange pigmentation of eyelids with periocular petechiae and mild macroglossia were observed. Incisional biopsies of the eyelids, cheeks and hands were obtained. The pathological study demonstrated amyloid deposits. Since protein electrophoresis was normal, the diagnosis of AA amyloidosis was postulated.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d184d9b0b3abefb86cb22f4d0a3656bd https://doi.org/10.4067/s0034-98872012000400011 Zobrazit plný text záznamu