Effect of endotoxin administration in pregnant camels
| Autor: | A.M. Homeida, A.M. AL-Dughaym |
|---|---|
| Jazyk: | angličtina |
| Předmět: |
medicine.medical_specialty
endocrine system Prostaglandin Metabolite Luteal phase Abortion Cortisol chemistry.chemical_compound Endotoxin Camels Pregnancy Internal medicine medicine Secretion reproductive and urinary physiology Progesterone Agricultural and Biological Sciences(all) business.industry medicine.disease Endocrinology chemistry Plasma concentration Original Article General Agricultural and Biological Sciences business |
| Zdroj: | Saudi Journal of Biological Sciences. (2):101-103 |
| ISSN: | 1319-562X |
| DOI: | 10.1016/j.sjbs.2010.02.002 |
| Popis: | Intravenous administration of Escherichia coli endotoxin at a dose of 0.05μg/kg bodyweight to pregnant camels resulted in abortion. The injection of endotoxin caused significant increases in the plasma concentration of 13,14-dihydro-15-prostaglandin F2α, the metabolite of prostaglandin F2α (PG F2α) and cortisol and a significant decrease in the concentration of progesterone. It is suggested that endotoxin caused abortion in camels was a consequence of endotoxin induced PG F2α secretion resulting in luteal regression and decreased progesterone concentration. |
| Databáze: | OpenAIRE |
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