Characteristics of Misclassified CT Perfusion Ischemic Core in Patients with Acute Ischemic Stroke
| Autor: | Sjoerd F. M. Jenniskens, Clean trial investigators, Jordi Borst, Henk A. Marquering, Ralph R. E. G. Geuskens, Wim H. van Zwam, Yvo B.W.E.M. Roos, Marit Lucas, A. M. Merel Boers, Diederik W.J. Dippel, Marianne A. A. van Walderveen, Olvert A. Berkhemer, Charles B. L. M. Majoie |
|---|---|
| Přispěvatelé: | Biomedical Engineering and Physics, Other departments, ACS - Amsterdam Cardiovascular Sciences, ANS - Amsterdam Neuroscience, Radiology and Nuclear Medicine, Neurology, RS: CARIM - R3 - Vascular biology, MUMC+: DA BV Medisch Specialisten Radiologie (9) |
| Rok vydání: | 2015 |
| Předmět: |
SELECTION
medicine.medical_specialty PENUMBRA Science viruses Blood volume Perfusion scanning Brain Ischemia Brain ischemia Text mining THEORETIC BASIS MAPS Image Processing Computer-Assisted Humans Medicine PART 1 heterocyclic compounds Stroke Blood Volume Multidisciplinary business.industry Penumbra Other Research Radboud Institute for Health Sciences [Radboudumc 0] COMPUTED-TOMOGRAPHY PERFUSION medicine.disease Perfusion enzymes and coenzymes (carbohydrates) Cerebral blood flow CEREBRAL-BLOOD-FLOW TECHNICAL IMPLEMENTATIONS INFARCT VOLUME Radiology Tomography X-Ray Computed business Nuclear medicine BRAIN PERFUSION Research Article |
| Zdroj: | PLoS One, 10 PLoS One, 10, 11 PLoS ONE, 10(11). Public Library of Science PLoS One (print), 10(11). Public Library of Science PLoS ONE, 10(11):e0141571. PUBLIC LIBRARY SCIENCE PLoS ONE, Vol 10, Iss 11, p e0141571 (2015) PLOS ONE, 10(11):e0141571. Public Library of Science PLoS ONE |
| ISSN: | 1932-6203 |
| Popis: | Contains fulltext : 152013.PDF (Publisher’s version ) (Open Access) BACKGROUND: CT perfusion (CTP) is used to estimate the extent of ischemic core and penumbra in patients with acute ischemic stroke. CTP reliability, however, is limited. This study aims to identify regions misclassified as ischemic core on CTP, using infarct on follow-up noncontrast CT. We aim to assess differences in volumetric and perfusion characteristics in these regions compared to areas that ended up as infarct on follow-up. MATERIALS AND METHODS: This study included 35 patients with >100 mm brain coverage CTP. CTP processing was performed using Philips software (IntelliSpace 7.0). Final infarct was automatically segmented on follow-up noncontrast CT and used as reference. CTP and follow-up noncontrast CT image data were registered. This allowed classification of ischemic lesion agreement (core on CTP: rMTT>/=145%, aCBV |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|