Effectiveness of Prostaglandin E 1 in Relieving Obstruction in Coarctation of the Aorta Without Opening the Ductus Arteriosus
| Autor: | J. J. Lamberti, Patrick A. Flynn, W. M. Gersony, Thomas J. Starc, Leonardo Liberman, R. S. Cooper |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
Male
congenital hereditary and neonatal diseases and abnormalities medicine.medical_specialty Coarctation of the aorta Arterial Occlusive Diseases Aortic Coarctation Constriction chemistry.chemical_compound medicine.artery Internal medicine Ductus arteriosus medicine Humans cardiovascular diseases Alprostadil Prostaglandin E1 Fetus Aorta business.industry Infant Newborn Infant Blood flow medicine.disease Cardiac surgery Treatment Outcome medicine.anatomical_structure chemistry embryonic structures Pediatrics Perinatology and Child Health cardiovascular system Cardiology Female Cardiology and Cardiovascular Medicine business |
| Zdroj: | Pediatric Cardiology. 25:49-52 |
| ISSN: | 1432-1971 0172-0643 |
| DOI: | 10.1007/s00246-003-0549-5 |
| Popis: | The two main theories regarding the pathogenesis of coarctation of the aorta are the Skodaic hypothesis of ductal tissue constricting the aorta at the level of the insertion of the ductus arteriosus and the flow theory of decreased ascending aortic blood flow in the fetus, which results in associated isthmic narrowing and a localized shelf. To document that ectopic ductal tissue constriction can cause coarctation of the aorta in the absence of a patent ductus arteriosus, we report three cases of infants presenting with critical coarctation who responded to prostaglandin E1 infusion without opening the ductus arteriosus. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink