Electrophysiological findings in a case of severe intrathecal baclofen overdose
| Autor: | Leopold Saltuari, Markus Kofler, K. Berek, Erich Schmutzhard, Franz Aichner, Lothar Russegger, Holger Baumgartner |
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| Rok vydání: | 1992 |
| Předmět: |
Male
Baclofen Adolescent Stimulation Normal values Somatosensory system chemistry.chemical_compound Evoked Potentials Somatosensory Reaction Time Medicine Humans Spasticity Evoked Potentials Injections Spinal business.industry General Neuroscience Muscles Electroencephalography Intrathecal baclofen Median nerve Electric Stimulation Electrophysiology chemistry Anesthesia Neurology (clinical) medicine.symptom Drug Overdose business |
| Zdroj: | Scopus-Elsevier |
| ISSN: | 0013-4694 |
| Popis: | Multimodality evoked potentials were examined in a case of serious accidental intrathecal baclofen overdose in a patient who suffered from severe spasticity due to a traumatic brain lesion. Electrophysiological findings during, before and after the intoxication were compared. Transcranial electrical stimulation up to 750 V did not evoke any responses in thenar muscles on the first day of intoxication. An improvement to normal values was observed within 3 days, paralleled by an amelioration of the patient's clinical condition. Cervical electrical stimulation was largely unaffected by baclofen. Median nerve somatosensory and brain-stem acoustic evoked potentials revealed few or no differences during intoxication compared to pre- and post-intoxication responses. |
| Databáze: | OpenAIRE |
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