Ocular Biometric Characteristics of Chinese with History of Acute Angle Closure
Autor: | Fei Yuan, Yifan Feng, Dong Chunqiong, Niu Weiran, Xi Zhang |
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Jazyk: | angličtina |
Rok vydání: | 2018 |
Předmět: |
medicine.medical_specialty
Biometrics genetic structures Article Subject Acute angle Population Logistic regression 03 medical and health sciences 0302 clinical medicine lcsh:Ophthalmology Ophthalmology medicine Risk factor education education.field_of_study Receiver operating characteristic business.industry Curve analysis Crowding lcsh:RE1-994 030221 ophthalmology & optometry sense organs business 030217 neurology & neurosurgery Research Article |
Zdroj: | Journal of Ophthalmology Journal of Ophthalmology, Vol 2018 (2018) |
ISSN: | 2090-004X |
DOI: | 10.1155/2018/5835791 |
Popis: | Purpose. To investigate the biometric characteristics of Chinese patients with a history of acute angle closure (AAC). Methods. In this clinic-based, retrospective, observational, cross-sectional study, biometric parameters of eyes were acquired from a general population of Chinese adults. The crowding value (defined as lens thickness (LT); central corneal thickness (CCT); anterior chamber depth (ACD)/axial length (AL)) was calculated for each patient. Logistic regression analysis was performed to identify risk factors for AAC. Receiver operating characteristic (ROC) curves were plotted, and biometric variables were compared to compile a risk assessment for AAC. Result. This study included 1500 healthy subjects (2624 eyes, mean age of 66.54 ± 15.82 years) and 107 subjects with AAC (202 eyes, mean age of 70.01 ± 11.05 years). Eyes with AAC had thicker lens (P≤0.001), shallower anterior chamber depth (P≤0.001), and shorter axial length (P≤0.001) than healthy eyes. Logistic regression analysis and ROC curve analysis indicated that a crowding value above 0.13 was a significant (P<0.05) risk factor for the development of AAC. Conclusions. Biometric parameters were significantly different between the eyes from the AAC group to the normal group. Ocular crowding value might be a new noncontact screening method to assess the risk of AAC in adults. |
Databáze: | OpenAIRE |
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