| Autor: |
Ingrid, Valencia Lozano, George, Dedes, Steve, Peterson, Dennis, Mackin, Andreas, Zoglauer, Sam, Beddar, Stephen, Avery, Jerimy, Polf, Katia, Parodi |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Zeitschrift für Medizinische Physik. |
| ISSN: |
0939-3889 |
| Popis: |
Compton-based prompt gamma (PG) imaging is being investigated by several groups as a potential solution for in vivo range monitoring in proton therapy. The performance of this technique depends on the detector system as well as the ability of the reconstruction method to obtain good spatial resolution to establish a quantitative correlation between the PG emission and the proton beam range in the patient. To evaluate the feasibility of PG imaging for range monitoring, we quantitatively evaluated the emission distributions reconstructed by a Maximum Likelihood Expectation Maximization (MLEM) and a Stochastic Origin Ensemble (SOE) algorithm. To this end, we exploit experimental and Monte Carlo (MC) simulation data acquired with the Polaris-J Compton Camera (CC) prototype. The differences between the proton beam range (R |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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