Narrowband Imaging for p16+ Unknown Primary Squamous Cell Carcinoma Prior to Transoral Robotic Surgery
| Autor: | C. Arturo Solares, Kelly Summers, Jonathan J. Beitler, James M. Hamilton, Ashley H. Aiken, Kelly R. Magliocca, Mark W. El-Deiry, Mihir R. Patel, Brian J. Boyce, Kareem Al-Mulki, H. Michael Baddour, Azeem S Kaka, Nabil F. Saba |
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| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty 03 medical and health sciences Narrow Band Imaging 0302 clinical medicine Robotic Surgical Procedures Transoral robotic surgery Carcinoma Medicine Humans Basal cell In patient 030223 otorhinolaryngology Cyclin-Dependent Kinase Inhibitor p16 Not evaluated business.industry Middle Aged medicine.disease Primary tumor Head and neck squamous-cell carcinoma Oropharyngeal Neoplasms Otorhinolaryngology 030220 oncology & carcinogenesis Unknown primary Carcinoma Squamous Cell Neoplasms Unknown Primary Surgery Female Radiology business |
| Zdroj: | Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. 163(6) |
| ISSN: | 1097-6817 |
| Popis: | Our purpose was to assess the potential utility of narrowband imaging (NBI) as a tool in diagnosing and treating unknown primary oropharyngeal squamous cell carcinoma (OPSCC) in patients prior to diagnostic resection with transoral robotic surgery (TORS). Between 2016 and March 2019, 29 patients with carcinoma of unknown primary meeting inclusion criteria were identified and treated with TORS. NBI was used preoperatively in 9 of 29 patients. A suspected tumor site was delineated by NBI in 8 of 9 patients (89%). Of the patients imaged with NBI, 8 of 9 (89%) patients had a pathologically confirmed tumor following TORS, corresponding to the same 8 suspected tumor sites identified with NBI. In contrast, a primary tumor was localized following TORS in 15 of 20 (75%) patients not evaluated with NBI. Thus, we see NBI as a potentially useful tool for the diagnosis and management of p16+ carcinoma of unknown primary.Level of Evidence: IIb. |
| Databáze: | OpenAIRE |
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