Peculiarities of the Functional State of Mitochondria of Peripheral Blood Leukocytes in Patients with Acute Myocardial Infarction
Autor: | Т. Yu. Rebrova, L. P. Tsapko, М. V. Golubenko, S. А. Afanas’ev, М. А. Kercheva, E. F. Muslimova |
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Rok vydání: | 2020 |
Předmět: |
Male
0301 basic medicine medicine.medical_specialty Myocardial Infarction Oxidative phosphorylation Mitochondrion Cell Fractionation Oxidative Phosphorylation General Biochemistry Genetics and Molecular Biology 03 medical and health sciences Oxygen Consumption 0302 clinical medicine Internal medicine Healthy volunteers medicine Humans In patient Myocardial infarction business.industry General Medicine Middle Aged medicine.disease Peripheral blood Mitochondria Adenosine Diphosphate 030104 developmental biology Endocrinology Case-Control Studies Leukocytes Mononuclear Phosphorylation Female business 030217 neurology & neurosurgery |
Zdroj: | Bulletin of Experimental Biology and Medicine. 169:435-437 |
ISSN: | 1573-8221 0007-4888 |
DOI: | 10.1007/s10517-020-04903-9 |
Popis: | We studied the rate of oxygen consumption by mitochondria isolated from peripheral blood leukocytes of patients with acute myocardial infarction and healthy volunteers. It was found that leukocyte mitochondria in patients with acute myocardial infarction were characterized by significantly lower rate of oxygen consumption and lower level of coupling of oxidation and phosphorylation processes in comparison with mitochondria from healthy volunteers. |
Databáze: | OpenAIRE |
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