Lewis Acid-Promoted [2+2] Cycloadditions of Alkenes with Arylketenes
| Autor: | Christopher M. Rasik, E. M. Rigsbee, A. Z. Spitz, M. K. Brown, C. Zhou, A. J. Nichols |
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| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Natural product
010405 organic chemistry Aryl Organic Chemistry Ketene 010402 general chemistry Bioinformatics 01 natural sciences Biochemistry Cycloaddition Article 0104 chemical sciences chemistry.chemical_compound chemistry Organic chemistry Lewis acids and bases Physical and Theoretical Chemistry |
| Popis: | A method for the [2 + 2] cycloaddition of aryl ketenes and alkenes is presented. The process involves the in situ generation of a ketene in the presence of a Lewis acid. The utility of products is demonstrated towards the synthesis of a common scaffold found in several natural product families. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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