Approximately independent linkage disequilibrium blocks in human populations

Autor:	Tomaz Berisa, Joseph K. Pickrell
Rok vydání:	2015
Předmět:	Genetic Markers Statistics and Probability Linkage disequilibrium Computer science Genomics Genome-wide association study Computational biology Biology 01 natural sciences Biochemistry Genome Linkage Disequilibrium 010104 statistics & probability 03 medical and health sciences 0302 clinical medicine Humans natural sciences 0101 mathematics Association mapping Molecular Biology 030304 developmental biology Genetic association Genetics 0303 health sciences Genome Human Chromosome Mapping Tag SNP Applications Notes 3. Good health Computer Science Applications Computational Mathematics Computational Theory and Mathematics Genetic marker Human genome Algorithms Software 030217 neurology & neurosurgery Genome-Wide Association Study
Zdroj:	Bioinformatics. 32:283-285
ISSN:	1367-4811 1367-4803
DOI:	10.1093/bioinformatics/btv546
Popis:	Summary: We present a method to identify approximately independent blocks of linkage disequilibrium in the human genome. These blocks enable automated analysis of multiple genome-wide association studies. Availability and implementation: code: http://bitbucket.org/nygcresearch/ldetect; data: http://bitbucket.org/nygcresearch/ldetect-data. Contact: tberisa@nygenome.org Supplementary information: Supplementary data are available at Bioinformatics online.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d14fe25b9f5bff0cb1dc378c61d54af6 https://doi.org/10.1093/bioinformatics/btv546 Zobrazit plný text záznamu