The interaction of an anti-lipid antibody (TEPC 15) with a model biomembrane system (monolayer)
| Autor: | Jack A. Lucy, Dennis Chapman, Gerardo D. Fidelio, Maria A. Urbaneja |
|---|---|
| Rok vydání: | 1987 |
| Předmět: |
Phosphatidylethanolamine
biology Phosphorylcholine Surface Properties Phosphatidylethanolamines Biophysics Phospholipid Biological membrane Membranes Artificial Cell Biology Surface pressure Biochemistry Antibodies chemistry.chemical_compound Membrane Lipids chemistry Phosphatidylcholine Monolayer biology.protein Phosphatidylcholines lipids (amino acids peptides and proteins) Antibody |
| Zdroj: | Biochimica et biophysica acta. 898(2) |
| ISSN: | 0006-3002 |
| Popis: | The interaction which occurs between an anti-lipid antibody (TEPC 15) and two phospholipids, phosphatidylcholine and phosphatidylethanolamine, when they are arranged in a lipid monolayer system has been studied. It is shown that the antibody is stabilised under the influence of a high lateral pressure when it is mixed with a lipid monolayer and that the behaviour of the antibody depends upon the lipid used. Measurements of the surface pressure and surface potential parameters of the lipid monolayers indicate that the antibody interacts differently with phosphatidylcholine compared with phosphatidylethanolamine. The antibody also exhibits a different interaction when it is pretreated with phosphorylcholine prior to being spread with a phosphatidylcholine monolayer. The interaction of the antibody with phosphatidylcholine-cholesterol monolayers has also been studied. |
| Databáze: | OpenAIRE |
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