Relationship of the cornea and globe dimensions to the changes in adult human crystalline lens diameter, thickness and power with age
| Autor: | Jean-Marie A. Parel, Fabrice Manns, Arthur Ho, Ashik Mohamed, Robert C. Augusteyn, Sushma Nandyala |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Adult Male medicine.medical_specialty Aging Biometry genetic structures Eye Refraction Ocular Article Cornea 03 medical and health sciences Cellular and Molecular Neuroscience Young Adult 0302 clinical medicine Ciliary body Lens thickness Ophthalmology Lens Crystalline medicine Humans Aged High magnification business.industry Eye refraction Accommodation Ocular Eye bank Organ Size Middle Aged eye diseases Sensory Systems Sclera 030104 developmental biology medicine.anatomical_structure Lens (anatomy) 030221 ophthalmology & optometry Female sense organs business |
| Zdroj: | Exp Eye Res |
| Popis: | It is well known that human crystalline lens shape, dimensions and optical properties change throughout life and influence whole eye refraction. However, it is not clear if lens properties are associated with other ocular parameters. The purpose of the present study was to investigate the relationship of corneal and external globe dimensions with adult lens diameter (LD), lens thickness (LT) and lens power (LP) in order to determine if external factors influence lens properties. Postmortem human eyes (n = 66, age = 20-78 years) were obtained from the Ramayamma International Eye Bank, Hyderabad, India. Globe antero-posterior length (GAPL) and mean (average of horizontal and vertical) diameters of cornea (MCD) and globe (MGD) were measured using digital calipers. Eyes were dissected to produce ocular structures that contain the lens maintained in its accommodating framework, including intact zonules, ciliary body and sections of sclera. Specimens were mounted in a mechanical lens stretching system. LD, LT and LP were measured using high magnification retro-illumination photography, slit illumination photography and Scheiner principle-based optical system respectively in the unstretched (accommodated) state. Relationships between external globe and corneal dimensions and LD, LT or LP were assessed by multiple regression analysis. Age (0.012 ± 0.003 mm/year; p |
| Databáze: | OpenAIRE |
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