BIOCHEMICAL CHANGES IN MALIGNANT HYPERPYREXIA
| Autor: | M. C. Hudson, P. Zapf, Michael A. Denborough, J. F. A. Forster, N. G. Carter |
|---|---|
| Rok vydání: | 1970 |
| Předmět: |
Male
Pathology medicine.medical_specialty Fever Potassium Physiology chemistry.chemical_element Anesthesia General Muscle damage Phosphates Drug Hypersensitivity chemistry.chemical_compound Humans Medicine Aspartate Aminotransferases Creatine Kinase Ornithine Carbamoyltransferase L-Lactate Dehydrogenase biology business.industry Muscles General Medicine Middle Aged Phosphate chemistry Biochemistry Susceptible individual biology.protein Creatine kinase business |
| Zdroj: | The Lancet. 295:1137-1138 |
| ISSN: | 0140-6736 |
| DOI: | 10.1016/s0140-6736(70)91214-6 |
| Popis: | Biochemical estimations in a fatal case of malignant hyperpyrexia showed very high serum-levels of creatine phosphokinase, phosphate, and potassium. These changes, together with pyrexia, could all have resulted from severe muscle damage induced by the anaesthetic agents in a susceptible individual. The high. serum-phosphate level led to a secondary fall in serum-calcium. |
| Databáze: | OpenAIRE |
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