Effects of age and sex on basal and dopamine-inhibited in vitro prolactin release, and dopamine receptor binding, by the rat adenohypophysis
| Autor: | G. S. Roth, K. Kochman, M. A. Kowatch, Marc R. Blackman |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
Male
Aging medicine.medical_specialty Dopamine Biology Receptors Dopamine Basal (phylogenetics) Sex Factors Pituitary Gland Anterior Internal medicine medicine Animals Secretion Rats Wistar Receptor Cells Cultured Age Factors Dopamine receptor binding Prolactin In vitro Rats Endocrinology Spiperone Dopamine receptor Female Geriatrics and Gerontology medicine.drug |
| Zdroj: | Aging Clinical and Experimental Research. 5:349-356 |
| ISSN: | 1720-8319 1594-0667 |
| DOI: | 10.1007/bf03324186 |
| Popis: | We measured basal and dopamine-inhibited pituitary cell prolactin (PRL) release in vitro, and dopamine receptor binding in pituitary homogenates, from intact male and female Wistar rats of varying ages. During 48–72 hours in culture, the baseline secretion rate of PRL from pituitary cells of old (24 months) male rats was less than one-half that from cells of mature (6 months) male rats, whereas the corresponding basal secretion rate of PRL from cells of old female rats was nearly 3-fold greater than that from cells of mature female rats (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink