The microINR portable coagulometer:analytical quality and user-friendliness of a PT (INR) point-of-care instrument
| Autor: | Pia Bükmann Larsen, Åsne Bakke, Jesper Revsholm, Elin Storjord, Kristin Husby, Grete Monsen, Tone Bukve, Rie McGrail, Mikael Christensen, Aslaug Johanne Risøy, Unni Marie Skålsvik, Heidi Strand, Joakim Eikeland, Jan Nybo, Elvar Theodorsson, Mette Fogh Møller, Solveig Meier Mikaelsen, Vegar Engeland Haugen, Reyes Serrano Teruel |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Pediatrics
medicine.medical_specialty Point-of-Care Systems Point-of-care testing Clinical Biochemistry Medical laboratory User friendliness 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine medicine PROTHROMBIN TIMES Humans Outpatient clinic International Normalized Ratio 030212 general & internal medicine OWREN International normalized ratio quality control Blood Coagulation Point of care Automation Laboratory Prothrombin time CALIBRATION Analysis of Variance medicine.diagnostic_test Norway business.industry Warfarin Anticoagulants Reproducibility of Results General Medicine Laboratories Hospital University hospital warfarin point-of-care testing Emergency medicine Prothrombin Time business ANTICOAGULANT-THERAPY medicine.drug point-of-care systems |
| Zdroj: | Larsen, P B, Storjord, E, Bakke, Å, Bukve, T, Christensen, M, Eikeland, J, Haugen, V E, Husby, K, McGrail, R, Mikaelsen, S M, Monsen, G, Møller, M F, Nybo, J, Revsholm, J, Risøy, A J, Skålsvik, U M, Strand, H, Teruel, R S & Theodorsson, E 2017, ' The microINR portable coagulometer : analytical quality and user-friendliness of a PT (INR) point-of-care instrument ', Scandinavian Journal of Clinical & Laboratory Investigation, vol. 77, no. 2, pp. 115-121 . https://doi.org/10.1080/00365513.2016.1277433 Larsen, P B, Storjord, E, Bakke, A, Bukve, T, Christensen, M, Eikeland, J, Haugen, V E, Husby, K, McGrail, R, Mikaelsen, S M, Monsen, G, Moller, M F, Nybo, J, Revsholm, J, Risoy, A J, Skalsvik, U M, Strand, H, Teruel, R S & Theodorsson, E 2017, ' The microINR portable coagulometer : analytical quality and user-friendliness of a PT (INR) point-of-care instrument ', Scandinavian Journal of Clinical and Laboratory Investigation. Supplement, vol. 77, no. 2, pp. 115-121 . https://doi.org/10.1080/00365513.2016.1277433 |
| Popis: | Regular measurement of prothrombin time as an international normalized ratio PT (INR) is mandatory for optimal and safe use of warfarin. Scandinavian evaluation of laboratory equipment for primary health care (SKUP) evaluated the microINR portable coagulometer (microINR(®)) (iLine Microsystems S.L., Spain) for measurement of PT (INR). Analytical quality and user-friendliness were evaluated under optimal conditions at an accredited hospital laboratory and at two primary health care centres (PHCCs). Patients were recruited at the outpatient clinic of the Laboratory of Medical Biochemistry, St Olav's University Hospital, Trondheim, Norway (n = 98) and from two PHCCs (n = 88). Venous blood samples were analyzed under optimal conditions on the STA-R(®)Evolution with STA-SPA + reagent (Stago, France) (Owren method), and the results were compared to capillary measurements on the microINR(®). The imprecision of the microINR(®) was 6% (90% CI: 5.3-7.0%) and 6.3% (90% CI: 5.1-8.3) in the outpatient clinic and PHCC2, respectively for INR ≥2.5. The microINR(®) did not meet the SKUP quality requirement for imprecision ≤5.0%. For INR |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|