ANNA-2: an antibody associated with paraneoplastic opsoclonus in a patient with large-cell carcinoma of the lung with neuroendocrine features--correlation of clinical improvement with tumor response

Autor:	Saadah Alrajab, Candis Morrison, Bong Kim, Rodrigo B Erlich, Mark R. Gilbert
Rok vydání:	2004
Předmět:	Cancer Research Pathology medicine.medical_specialty Lung Neoplasms Antibodies Neoplasm Tumor response Carcinoma Non-Small-Cell Lung Antineoplastic Combined Chemotherapy Protocols medicine Carcinoma Humans Lung biology business.industry Large cell Antibody titer General Medicine Opsoclonus Middle Aged medicine.disease Prognosis medicine.anatomical_structure Treatment Outcome Oncology Symptom improvement Antibodies Antinuclear biology.protein Female Antibody business Paraneoplastic Syndromes Nervous System
Zdroj:	Cancer investigation. 22(2)
ISSN:	0735-7907
Popis:	This report describes a case of large-cell lung carcinoma with neuroendocrine features, presenting with the full clinical picture of paraneoplastic opsoclonus-myoclonus syndrome. The patient had an unexpectedly dramatic resolution of the neurologic dysfunction after receiving antineoplastic treatment. Symptom improvement paralleled a progressive decline of serum ANNA-2 antibody titers to undetectable levels.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d11cd196ef1ca5c3355fe279dd77113d https://pubmed.ncbi.nlm.nih.gov/15199608 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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