Genitourinary abnormalities in an asymptomatic screening population: findings on virtual colonoscopy
| Autor: | Brian K. Auge, James O. L'Esperance, Dane R Lacey, Jason M. Durbin, Sean P. Stroup, Hernan O. Altamar |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Adult
Male medicine.medical_specialty Population Colonoscopy Risk Assessment Asymptomatic Predictive Value of Tests Risk Factors medicine Humans Clinical significance Prospective Studies education Prospective cohort study Aged Incidental Findings education.field_of_study medicine.diagnostic_test Genitourinary system business.industry Incidence Incidence (epidemiology) General Medicine Middle Aged Female Urogenital Diseases United States Surgery Nephrology Predictive value of tests Asymptomatic Diseases Female Radiology medicine.symptom business Colonography Computed Tomographic |
| Zdroj: | Clinical Nephrology. 77:204-210 |
| ISSN: | 0301-0430 |
| DOI: | 10.5414/cn107242 |
| Popis: | The true incidences of genitourinary conditions in the modern era are not completely known. We sought to determine the incidence of genitourinary abnormalities in a group of asymptomatic adult patients undergoing axial imaging with virtual colonoscopy.We performed a post-hoc analysis of imaging results from a prospective, IRB-approved study that randomized patients to screening "virtual" CT colonography (CTC) followed by standard endoscopic colonoscopy. CTC scans were reviewed separately by an independent radiologist and a urologist for genitourinary abnormalities. Genitourinary abnormalities were characterized as of minor, moderate, or major clinical significance. Identified nephroliths were categorized by location, laterality, size, and number. Student's t-tests and Fisher's exact-tests were used for continuous and categorical variables as appropriate.Of 490 patients undergoing CTC and eligible for analysis, no genitourinary abnormalities were found in 294 (60%), minor genitourinary abnormalities were found in 100 (20.4%), moderate genitourinary abnormalities were found in 86 (17.6%), and major genitourinary abnormalities were found in 10 (2%). Renal cysts (n = 60, 12%) were the most common minor urologic findings. Moderate and major genitourinary findings of nephrolithiasis, adrenal adenomas, and renal masses were noted in 13.9%, 3%, and 2% of the population, respectively. The largest stone was 1.2 cm, and the smallest was 1 mm; while 59% had stones3mm, 20% between 3 mm and 5 mm, 18% between 5 mm and 10 mm, and 3%10 mm in size. Unilateral stones were found in 85%, while bilateral were found in 15%, and the average number of stones was 2, (range 1 - 16). Age and male sex were significantly associated with moderate or major genitourinary findings p = 0.04 and p = 0.05, respectively.CT colonography in an asymptomatic screening population helped to identify nephrolithiasis in 13.9%. Moderate and major urologic abnormalities were found in 20% of the cohort. Risk factors included male sex and older age. |
| Databáze: | OpenAIRE |
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