Experimental study on maintaining the curvature of transplanted cartilage: Influence of the number of cartilage struts
| Autor: | Hideaki Rikimaru, Yukiko Rikimaru-Nishi, Koichi Watanabe, Tomonosin Kanazawa, Kensuke Kiyokawa, Shinichiro Hashiguchi, Aritaka Sakamoto, Kei-ichiro Nakamura |
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| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty Polyglycolic acid suture Biocompatible Materials 030230 surgery Rats Sprague-Dawley 03 medical and health sciences Fixation (surgical) Postoperative Complications 0302 clinical medicine medicine Animals Congenital Microtia Sutures business.industry Cartilage Suture Techniques Microtia 030206 dentistry Anatomy medicine.disease Costal cartilage Surgery Costal Cartilage Fibrous connective tissue Disease Models Animal surgical procedures operative medicine.anatomical_structure Absorbable sutures business Contact area Polyglycolic Acid |
| Zdroj: | Journal of Plastic, Reconstructive & Aesthetic Surgery. 72:1340-1346 |
| ISSN: | 1748-6815 |
| DOI: | 10.1016/j.bjps.2019.03.039 |
| Popis: | Summary Background When auriculoplasty is performed for microtia, wire often becomes exposed during the long postoperative period. We have investigated other materials for fixing cartilage. We previously reported that absorbable sutures are more appropriate than wire. The present animal experiments investigated the reasons why fixation of transplanted cartilage is maintained when using absorbable sutures. Methods The costal cartilages of Sprague-Dawley rats were harvested, and three cartilage transplant models were prepared. After bending a costal cartilage into a U-shape, it was fixed by using only absorbable sutures as the control or was fixed by suturing one or two cross struts of cartilage to the U-shaped graft. Then the cartilages were subcutaneously transplanted into the backs of the rats. They were removed 8 weeks later, and the return rate of the bent cartilages was assessed. Results The return rate was 74.0%, in the suture-only group (control), 27.9% in the one-strut group, and 8.3% in the two-strut group. When the sites of contact between the U-shaped graft and the cartilage struts were observed by light microscopy, adhesion of the two cartilages by fibrous connective tissue was observed. Conclusion U-shaped cartilage grafts demonstrated a smaller return rate when there was a larger contact area with the cartilage struts. Each strut was fixed by fibrous connective tissue at the contact site, thereby maintaining the shape of the graft. Thus, when creating a cartilage framework, it is important to fix the bent cartilage to the cartilage struts with a sufficiently large contact area. |
| Databáze: | OpenAIRE |
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