Geno- and cytotoxicity induced on Cyprinus carpio by aluminum, iron, mercury and mixture thereof
| Autor: | Youssef Paolo Mendoza-Zenil, R.C. Rodríguez Martín-Doimeadios, Nuria Rodríguez-Fariñas, Ricardo Pérez-Pastén Borja, Armando Elizalde-Velázquez, Hariz Islas-Flores, Leobardo Manuel Gómez-Oliván, Marcela Galar-Martínez, Sandra García-Medina, Nely SanJuan-Reyes, Ninfa Ramírez-Durán |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Carps Iron Health Toxicology and Mutagenesis chemistry.chemical_element 010501 environmental sciences medicine.disease_cause 01 natural sciences Cyprinus Industrial wastewater treatment 03 medical and health sciences Common carp medicine Animals Cytotoxicity 0105 earth and related environmental sciences Micronucleus Tests biology Caspase 3 Public Health Environmental and Occupational Health Mercury General Medicine biology.organism_classification Pollution Mercury (element) Comet assay 030104 developmental biology chemistry Environmental chemistry Micronucleus test Comet Assay Biomarkers Water Pollutants Chemical Genotoxicity Aluminum DNA Damage |
| Zdroj: | Ecotoxicology and Environmental Safety. 135:98-105 |
| ISSN: | 0147-6513 |
| Popis: | Metals such as Al, Fe and Hg are used in diverse anthropogenic activities. Their presence in water bodies is due mainly to domestic, agricultural and industrial wastewater discharges and constitutes a hazard for the organisms inhabiting these environments. The present study aimed to evaluate geno- and cytotoxicity induced by Al, Fe, Hg and the mixture of these metals on blood of the common carp Cyprinus carpio. Specimens were exposed to the permissible limits in water for human use and consumption according to the pertinent official Mexican norm [official Mexican norm NOM-127-SSA1-1994] Al (0.2mgL-1), Fe (0.3mgL-1), Hg (0.001mgL-1) and their mixture for 12, 24, 48, 72 and 96h. Biomarkers of genotoxicity (comet assay and micronucleus test) and cytotoxicity (caspase-3 activity and TUNEL assay) were evaluated. Significant increases relative to the control group (p |
| Databáze: | OpenAIRE |
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