Evaluation of resynchronization of contractile function following biventricular pacing using colour tissue doppler imaging
Autor: | M.J. Schalij, R. de Melker, E. E. van der Wall, Jeroen J. Bax, C. Adriaansche, P. J. Voogd, Thomas H. Marwick, Sander G. Molhoek, L. Van Erven |
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Rok vydání: | 2002 |
Předmět: |
medicine.medical_specialty
Ejection fraction business.industry Dilated cardiomyopathy Biventricular pacemaker medicine.disease Doppler imaging Nyha class QRS complex medicine.anatomical_structure Ventricle Internal medicine Heart failure medicine Cardiology Cardiology and Cardiovascular Medicine business circulatory and respiratory physiology |
Zdroj: | Journal of the American College of Cardiology. 39:356 |
ISSN: | 0735-1097 |
DOI: | 10.1016/s0735-1097(02)81599-6 |
Popis: | Biventdcular (BV) pacing is evaluated as an alternative treatment for patients with dilated cardiomyppathy (both ischemic and non-ischemic) and end-stage heart failure. Colour tissue Doppler imaging using echocardiography allows noninvasive, quantitative assessment of radial motion in the long-axis with measurement of peak systolic velocity timing. The aim of the present study was to evaluate quantitatively, the systolic performance of the left ventricle and the resynchrenization of contraction (before vs after implantation). Patients and methods: 25 patients with dilated cardiomyopathy (11 ischemic), NYHA class III or IV, QRS duration >120 ms received a biventricular pacemaker. Routine 2D echo and colour tissue Doppler imaging were performed before and within 1 week following implantation. LVEF was assessed using the biplane Sampson's method.Peak systolic velocity (PSV) and time to PSV (TPV) were assessed in 4 regions (basal anterior, inferior, lateral and septal). By averaging the TPV from all 4 regions, a synchronization index was dedved from these measurements. Reaults: LVEF improved by 9±9% following pacing; 17 patients improved LVEF 5% or more. The change in PSV in the septal and lateral regions related significantly to the change in LVEF (r=0.74, r=0.62).The change in synchronization index before vs after pacing (as a measurement of REsynchronization) was related to the change in LVEF (y=120x+5.6, r=0.79, P |
Databáze: | OpenAIRE |
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