Health Utilities Index Mark 3 (HUI3) demonstrated construct validity in a Nigerian population with hypertension

Autor: Obinna Ikechukwu Ekwunife, Cletus N. Aguwa, Nneka Uchenna Igboeli
Rok vydání: 2012
Předmět:
Zdroj: Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation. 22(2)
ISSN: 1573-2649
Popis: This study seeks to establish the construct validity of Health Utilities Index Mark 3 (HUI3)--a health state utility measure--in a Nigerian population of hypertensive patients.A descriptive cross-sectional study was conducted in a population of hypertensive patients in two tertiary hospitals located in South-Eastern Nigeria. A priori hypotheses were tested to establish construct validity.A total of 384 participants were interviewed. Hypertensive patients with stroke or coronary heart disease (CHD) had a lower overall utility value compared to those with hypertension alone. There was a significant difference in group means of 0.53 (95 % confidence interval of 0.44-0.62); t = 11.8, p0.01, between participants that had hypertension alone and participants with hypertension and stroke. Also, there was a significant difference in group means of 0.44 (95 % confidence interval of 0.34-0.56); t = 8.2, p0.01, between participants that had hypertension alone and participants with hypertension and CHD. Generally, there was a significant health-related quality of life deficit among patients with severe clinical variables compared to those with milder clinical variables.HUI3 demonstrated constructed validity among a population of Nigerian patients with high blood pressure.
Databáze: OpenAIRE