Hazardous genomic bioeffects of home Wi-Fi systems
Autor: | Sevgi Durna Daştan, Sinan Soylu, Mustafa Duman, Taner Daştan, Halime Hanım Pençe, Bülent Uyanık, Mustafa Turan, Atilla Kurt, Aydin Zilan |
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Přispěvatelé: | Dastan, S.D., Cumhuriyet University, Faculty of Veterinary Medicine, Department of Zootechnics and Animal Nutrition, Division of Biometry and Genetics, Sivas, Turkey -- Soylu, S., Cumhuriyet University, Faculty of Medicine, Department of General Surgery, Sivas, Turkey -- Pence, H.H., Department of Biochemistry, Saglik Bilimleri University School of Medicine, Istanbul, Turkey -- Uyanik, B., Bağcılar Education and Research Hospital, Department of Medical Genetics, Istanbul, Turkey -- Duman, M., Saglik Bilimleri University School of Medicine, Kartal Kosuyolu Yuksek Ihtisas Hospital, Department of Gastrointestinal Surgery, Istanbul, Turkey -- Kurt, A., Cumhuriyet University, Faculty of Medicine, Department of General Surgery, Sivas, Turkey -- Dastan, T., Bingol University, Faculty of Arts and Science, Department of Chemistry, Bingol, Turkey -- Zilan, A., Saglik Bilimleri University Bagcilar Education and Research Hospital, Department of General Surgery, Istanbul, Turkey -- Turan, M., Saglik Bilimleri University Bagcilar Education and Research Hospital, Department of General Surgery, Istanbul, Turkey, UYANIK, BÜLENT |
Jazyk: | angličtina |
Rok vydání: | 2018 |
Předmět: |
0301 basic medicine
Microarray Microarray analysis techniques Cognitive Neuroscience Total rna Dastan S. D. SOYLU S. Pence H. H. Uyanik B. Duman M. KURT A. Dastan T. Zilan A. Turan M. -Hazardous genomic bioeffects of home Wi-Fi systems- NeuroQuantology cilt.16 ss.12-19 2018 Rat brain Atomic and Molecular Physics and Optics Emf exposure Andrology 03 medical and health sciences 030104 developmental biology Developmental Neuroscience Wireless radiofrequency Gene expression Electromagnetic field MRNA Gene |
Popis: | Objective of this study is to investigate the changes of whole genom gene expression levels in rat brain induced by 2,4 GHz Wireless Fidelity Radiofrequency Electromagnetic Field (WiFi RF-EMF). Total RNA was extracted immediately and purified from the rat brain, after 12 hours/day exposed or sham-exposed to a frequency of 2,4 GHz WiFi RF-EMF for 14 days. Roche-Nimblegene-Agilent Microarray System was applied to investigate the changes of gene expression in rat brain. Roche-Nimblegene-Agilent Genespring Software for Microarray Analysis was used in bioenformatic analysis. After 14 days of WiFi RF-EMF exposure, 69 genes in experimental group showed statistical significant down regulation compared with the control group. Ten genes in experimental group showed statistical significant up regulation compared with the control group. In this study, it was detected that WiFi RF-EMF exposure to brain cells resulted with the down and up regulation of transcription level of some important genes. © 2018, Anka Publishers. All rights reserved. T-678 This work was supported by Cumhuriyet University BAP Fund with the Project Number T-678. |
Databáze: | OpenAIRE |
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