Phospholipid composition of subcellular fractions and phospholipid-exchange activity in chicken liver and MC-29 hepatoma
| Autor: | Tania Markovska, Atanas Boyanov, Heni Chelibonova-Lorer, Albena Momchilova, Ekaterina Gavazova, Tania Neicheva, Koumanov K |
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| Rok vydání: | 1982 |
| Předmět: |
Biophysics
Phospholipid Mitochondria Liver Mitochondrion Biochemistry chemistry.chemical_compound Endocrinology Liver Neoplasms Experimental Chicken Liver Phosphatidylcholine Animals Phospholipid Transfer Proteins Phospholipids Cell Membrane Membrane Proteins Sphingomyelins Membrane chemistry Liver Liposomes Microsome Microsomes Liver Phosphatidylcholines lipids (amino acids peptides and proteins) Composition (visual arts) Sphingomyelin Carrier Proteins Chickens Subcellular Fractions |
| Zdroj: | Biochimica et biophysica acta. 713(1) |
| ISSN: | 0006-3002 |
| Popis: | The phospholipid composition of mitochondria, microsomes and plasma membranes from liver and MC-29 hepatoma from White Leghorn chickens has been investigated. It was established that all mitochondria and microsome phospholipid fractions obtained from MC-29 hepatoma are increased strongly compared to those from liver. The sphingomyelin augmentation was particularly great. In hepatoma plasma membranes only the sphingomyelin quantity was increased. Sphingomyelin- and phosphatidylcholine-exchange activities were observed in avian liver for the first time. These two activities were increased in MC-29 hepatoma cells. Three phospholipid-exchange proteins have been established in chicken liver 105000 × g supernatant. One of them specifically transports phosphatidylcholine, the second one is non-specific for phosphatidylcholine and sphingomyelin, and the third one is specific only for sphingomyelin. In hepatoma cells only a non-specific phosphatidylcholine- and sphingomyelin-exchange protein was found. |
| Databáze: | OpenAIRE |
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