Protein bodies: how the ER deals with high accumulation of recombinant proteins

Autor:	Rima Menassa, Reza Saberianfar
Rok vydání:	2017
Předmět:	protein body 0301 basic medicine hydrophobin education elastin‐like polypeptide Plant Science Vacuole Protein tag Biology fusion tags Zera 03 medical and health sciences symbols.namesake Tobacco Organelle Storage protein Zera® Organelles chemistry.chemical_classification Endoplasmic reticulum food and beverages Golgi apparatus Plants Genetically Modified biology.organism_classification Recombinant Proteins endoplasmic reticulum 030104 developmental biology chemistry Biochemistry Protein body Commentary symbols Agronomy and Crop Science Biotechnology
Zdroj:	Plant Biotechnology Journal
ISSN:	1467-7644
DOI:	10.1111/pbi.12730
Popis:	Protein bodies (PBs) are highly specialized protein storage organelles in cereal seeds. PB formation in seeds initiates in the endoplasmic reticulum (ER), and depending on the plant species, PBs remain in the ER or find their way out of the ER, bypass the Golgi and end up in protein storage vacuoles (PSVs) (Khan et al., 2012). Protein bodies have been ectopically induced in leaves by producing high amounts of ER-retrieved recombinant proteins, usually by fusing them to protein tags such as Zera®, elastin-like polypeptide (ELP) and hydrophobin-I (HFBI). This article is protected by copyright. All rights reserved.
Databáze:	OpenAIRE
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