Coupled Secretion of Gastric Lipase and Pepsin in Man following Pentagastrin Stimulation
Autor: | Z. Szafran, H. Szafran, T. Popiela, G. Trompeter |
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Rok vydání: | 1978 |
Předmět: |
Adult
medicine.medical_specialty medicine.medical_treatment Stimulation Vagotomy fluids and secretions Pepsin Internal medicine medicine Humans Gastric lipase Secretion Lipase Gastric Acidity Determination Gastric Juice Dose-Response Relationship Drug biology Chemistry digestive oral and skin physiology Gastroenterology Hydrogen-Ion Concentration Middle Aged Pepsin A digestive system diseases Pentagastrin Endocrinology Duodenal Ulcer biology.protein Secretory Rate hormones hormone substitutes and hormone antagonists medicine.drug |
Zdroj: | Digestion. 18:310-318 |
ISSN: | 1421-9867 0012-2823 |
DOI: | 10.1159/000198218 |
Popis: | Secretion patterns of gastric lipase and pepsin were studied in duodenal ulcer patients before and after vagotomy and in healthy subjects following continuous administration of pentagastrin in graded doses. The lipase output increased in response to pentagastrin stimulation in similar fashion as that of pepsin. The output of the two enzymes were correlated with each other and with hydrogen ion output. Evaluation of dose-response relationships showed that in duodenal ulcer patients the secretion of gastric lipase and pepsin is more sensitive to pentagastrin stimulation than that of hydrogen ions. |
Databáze: | OpenAIRE |
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