Incidence, predictors and clinical outcome of early bleeding events in patients undergoing a left ventricular assist device implant
| Autor: | Sakir Akin, Jos A. Bekkers, Ad J.J.C. Bogers, Alina A. Constantinescu, Kadir Caliskan, Frank W.G. Leebeek, Jasper J. Brugts, Ozcan Birim, Jeroen J H Bunge, Usman Kashif, Rahatullah Muslem, Robert J. van Thiel |
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| Přispěvatelé: | Cardiology, Cardiothoracic Surgery, Intensive Care, Hematology |
| Rok vydání: | 2018 |
| Předmět: |
Pulmonary and Respiratory Medicine
Adult Male Reoperation medicine.medical_specialty medicine.medical_treatment 030204 cardiovascular system & hematology Postoperative Hemorrhage Prosthesis Implantation 03 medical and health sciences 0302 clinical medicine Extracorporeal Membrane Oxygenation Interquartile range Risk Factors Extracorporeal membrane oxygenation medicine Humans Survival rate Retrospective Studies business.industry Platelet Count Retrospective cohort study General Medicine Odds ratio Middle Aged Surgery Treatment Outcome 030228 respiratory system Ventricular assist device Female Heart-Assist Devices Cardiology and Cardiovascular Medicine business Packed red blood cells Complication Cardiomyopathies |
| Zdroj: | European Journal of Cardio-thoracic Surgery, 54(1), 176-182. Elsevier |
| ISSN: | 1873-734X 1010-7940 |
| Popis: | OBJECTIVES Bleeding is a common complication following left ventricular assist device (LVAD) implantation. The goal of this study was to investigate the incidence, predictors and clinical outcome of early bleeding events in patients after LVAD implantation. METHODS A total of 83 patients (age 50 ± 13 years, 76% men) had an LVAD implanted [77% HeartMate II, 19% HeartMate 3 (Abbott, Chicago, IL, USA)] over a period of 11 years. Patients were included consecutively. An early bleeding event was defined as the need for thoracic surgical re-exploration or transfusion with >4 units of packed red blood cells before discharge. RESULTS Overall, 39 (47%) patients (age 50 ± 14 years, 77% men) experienced an early bleeding event [median time 6 days (interquartile range 1-9 days)]. Furthermore, 10 (26%) of these patients had ≥2 bleeding events. Twelve of the 14 (92%) patients with venoarterial extracorporeal membrane oxygenation (ECMO) support before LVAD implantation experienced an early bleeding event versus 27 of the 69 (39%) patients without ECMO support (P |
| Databáze: | OpenAIRE |
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