Fish consumption and the risk of myocardial infarction and stroke in the German arm of the European Prospective Investigation into Cancer and Nutrition (EPIC-Germany)
Autor: | Heiner Boeing, Cornelia Weikert, Rudolf Kaaks, Tilman Kühn, Birgit Teucher, Brian Buijsse |
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Rok vydání: | 2013 |
Předmět: |
Adult
Male Percentile medicine.medical_specialty Myocardial Infarction Medicine (miscellaneous) EPIC Haemorrhagic stroke Eating Risk Factors Germany Internal medicine medicine Animals Humans Myocardial infarction Stroke Aged Nutrition and Dietetics business.industry Hazard ratio Fishes Feeding Behavior Middle Aged Nutrition Surveys medicine.disease Fish consumption Diet European Prospective Investigation into Cancer and Nutrition Cardiology Female business |
Zdroj: | British Journal of Nutrition. 110:1118-1125 |
ISSN: | 1475-2662 0007-1145 |
Popis: | Recent meta-analyses have confirmed that fish consumption is related to decreased risks of ischaemic stroke and fatal CHD, while there seem to be no clear associations between fish consumption and the risks of haemorrhagic stroke and non-fatal CHD. As no studies in German populations have been reported to date, we assessed whether fish consumption as recorded by FFQ between 1994 and 1998 was related to incident myocardial infarction (MI) and stroke within the German arm of the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Cox proportional hazards regression analyses were conducted based on the data of 48 315 participants aged 35–65 years at baseline. The median fish intake was 16·4 g/d (25th–75th percentile 8·2–28·8 g/d). During a mean follow-up of 8·1 years, 605 incident MI and 525 incident strokes have been documented. After multiple adjustment, fish consumption was not related to incident MI (hazard ratio (HR) 0·84, 95 % CI 0·66, 1·08, Ptrend= 0·21) or stroke (HR 0·96, 95 % CI 0·73, 1·26, Ptrend= 0·67). Separate analyses for fatal MI, ischaemic stroke and haemorrhagic stroke did not show significant associations, either. With regard to non-fatal MI, there was a non-significant trend for an inverse association (HR 0·78, 95 % CI 0·59, 1·03, Ptrend= 0·07). Overall, fish consumption was not related to the risks of MI and stroke in the EPIC-Germany study. |
Databáze: | OpenAIRE |
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