Origin of the vertebrate visual cycle: II. Visual cycle proteins are localized in whole brain including photoreceptor cells of a primitive chordate
| Autor: | Hideo Iwamoto, Motoyuki Tsuda, Takehiro Kusakabe, Masashi Nakagawa, Yuki Nakashima, Kiyotaka Okunou, Takeo Horie |
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| Rok vydání: | 2003 |
| Předmět: |
cis-trans-Isomerases
Opsin genetic structures Ascidian Chordate Chordata Nonvertebrate Retinal medicine Arrestin Animals Ciona intestinalis Eye Proteins In Situ Hybridization Brain Chemistry Retina biology Visual cycle Immunochemistry fungi Rod Opsins Proteins biology.organism_classification eye diseases Sensory Systems Cell biology Ciona Ophthalmology medicine.anatomical_structure RPE65 embryonic structures Photoreceptor Cells Invertebrate Photoisomerase sense organs Carrier Proteins Retinal Pigments Visual phototransduction |
| Zdroj: | Vision Research. 43(28):3045-3053 |
| ISSN: | 0042-6989 |
| DOI: | 10.1016/j.visres.2003.09.012 |
| Popis: | The visual cycle system in a primitive chordate, ascidian Ciona intestinalis, was studied by whole-mount in situ hybridization and by whole-mount immunohistochemistry. Three visual cycle proteins, Ciona homologue of RGR (Ci-opsin3), CRALBP (Ci-CRALBP), and BCO/RPE65 (Ci-BCO/RPE65) were widely distributed in the brain vesicle and visceral ganglion. To identify the visual cycle system in a primitive chordate, we compared the localization of photoreceptor-specific proteins (visual pigment and arrestin) and visual cycle proteins (Ci-opsin3 and Ci-CRALBP). The ascidian visual cycle is composed of two cellular compartments, the photoreceptors and the brain vesicle, but some photoreceptor cells also contain visual cycle proteins. |
| Databáze: | OpenAIRE |
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