Quantitative Ultrasound and Bone Mineral Density in Patients with Primary Hyperparathyroidism Before and after Surgical Treatment
| Autor: | Luigi Gennari, S Pacini, S. Gonnelli, Chiara Cepollaro, B. Rossi, Andrea Montagnani, Carlo Gennari, R. Monaco |
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| Rok vydání: | 2000 |
| Předmět: |
Adult
Male musculoskeletal diseases Parathyroidectomy medicine.medical_specialty Bone density Endocrinology Diabetes and Metabolism medicine.medical_treatment Bone and Bones Absorptiometry Photon Bone Density Bone mineral density medicine Humans Hyperparathyroidism Quantitative ultrasound Bone Resorption Aged Ultrasonography Bone mineral business.industry Ultrasound Middle Aged Hand musculoskeletal system medicine.disease Calcaneus Treatment Outcome Orthopedic surgery Female Radiology Nuclear medicine business Primary hyperparathyroidism Follow-Up Studies |
| Zdroj: | Osteoporosis International. 11:255-260 |
| ISSN: | 1433-2965 0937-941X |
| DOI: | 10.1007/s001980050289 |
| Popis: | The aim of this study was to assess the pattern of ultrasound (QUS) parameters and bone mineral density at different skeletal sites in patients with primary hyperparathyroidism (PHPT) before and after surgical treatment. In 22 patients (age range 28–74 years) with PHPT we measured speed of sound (SOS), attenuation (BUA) and Stiffness at the calcaneus, amplitude-dependent speed of sound (AD-SoS) at proximal phalanges, and bone mineral density at lumbar spine (BMD-LS) and at the mid-radius (BMD-MR) and ultradistal radius (BMD-UDR) before, 1 and 2 years after surgical operation. Twenty-two age- and sex-matched healthy subjects provided control data. Before surgery, all parameters apart from SOS were significantly lower in PHPT patients than in controls. At the end of the study period, BMD-LS increased by 7.0%, BMD-UDR by 7.4% and BMD-MR by 11.0%. The changes in ultrasound parameters after surgery were lower (0.44% for SOS, 2.2% for BUA, 3.3% for Stiffness and 2.6% for AD-SoS); however, the increase was statistically significant (p |
| Databáze: | OpenAIRE |
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