Hemophagocytic syndrome: A cause of pancytopenia in human ehrlichiosis
| Autor: | Craig Smith, K A Konkol, K C Abbott, T J O'Rourke, M Ristic, C J Holland, C K McAllister, S J Vukelja |
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| Rok vydání: | 1991 |
| Předmět: |
Male
Pathology medicine.medical_specialty Histiocytosis Non-Langerhans-Cell Pancytopenia Ehrlichia canis Bone Marrow hemic and lymphatic diseases medicine Humans Aged Cytopenia biology Septic shock Ehrlichia business.industry Ehrlichiosis Hematology medicine.disease biology.organism_classification Antibodies Bacterial Blood Cell Count Rickettsiosis Ehrlichiosis (canine) Immunology Hemophagocytosis business |
| Zdroj: | American Journal of Hematology. 38:230-234 |
| ISSN: | 1096-8652 0361-8609 |
| DOI: | 10.1002/ajh.2830380315 |
| Popis: | A 67-year-old white man with human ehrlichiosis infection complicated by pancytopenia, hemophagocytic syndrome, disseminated intravascular coagulopathy and septic shock is presented. The patient had been on a three-week camping trip to California, Colorado, Utah, and New Mexico. The diagnosis of human ehrlichiosis was confirmed by sixteen-fold rise in antibody titer to Ehrlichia canis, and supported by the characteristic cytoplasmic inclusions. Human ehrlichiosis should be considered in the differential diagnosis in patients with fever and cytopenia associated with hemophagocytosis. Pancytopenia associated with ehrlichiosis is transient; however, it may be severe, and appears to be associated with destruction of normal blood elements. |
| Databáze: | OpenAIRE |
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