Handheld diffuse reflectance spectroscopy system for noninvasive quantification of neonatal bilirubin and hemoglobin concentrations: a pilot study

Autor: Cheng, Nan-Yu, Tzeng, Shih-Yu, Fang, Ming-Chein, Kuo, Chun-Yen, Lu, Wen-Hsien, Yang, Chin-Chieh, Tseng, Sheng-Hao
Rok vydání: 2022
Předmět:
Zdroj: Biomed Opt Express
ISSN: 2156-7085
DOI: 10.1364/boe.475531
Popis: The prevalence rate of neonatal jaundice can reach 80%, of which 5% may develop dangerous hemolytic jaundice. The blood test for obtaining bilirubin and hemoglobin concentration is the gold standard for diagnosing hemolytic jaundice; however, frequently drawing blood from jaundice neonates for the screening purpose is not practical. We have developed a handheld diffuse reflectance spectroscopy system to noninvasively determine the bilirubin and hemoglobin levels in neonates. Our study showed that the correlation coefficients were 0.95 and 0.80 for bilirubin and hemoglobin between the results from the blood tests and our handheld system, respectively. This handheld system could be an effective tool for screening hemolytic jaundice.
Databáze: OpenAIRE