The Role of Late-Phase Pulse Inversion Harmonic Imaging in the Detection of Occult Hepatic Metastases
| Autor: | Mehmet Araç, Cem Yücel, Serap Gültekin, Hakan Ozdemir, Halil Celik, Suna Özhan Oktar |
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| Rok vydání: | 2006 |
| Předmět: |
Adult
Male medicine.medical_specialty Second-harmonic imaging microscopy Contrast Media Sensitivity and Specificity Lesion Iodinated contrast Polysaccharides Biopsy medicine Humans Radiology Nuclear Medicine and imaging Neoplasm Metastasis Radiation treatment planning Aged Ultrasonography Cancer staging Aged 80 and over Radiological and Ultrasound Technology medicine.diagnostic_test business.industry Liver Neoplasms Magnetic resonance imaging Middle Aged Magnetic Resonance Imaging Occult Female Radiology medicine.symptom business Tomography Spiral Computed |
| Zdroj: | Journal of Ultrasound in Medicine. 25:1139-1145 |
| ISSN: | 0278-4297 |
| Popis: | Objective. The purpose of this study was to investigate the efficacy of late-phase pulse inversion harmonic imaging (PIHI) in detecting occult metastases and to compare the results with helical computed tomography (CT) in a group of patients whose fundamental liver sonographic results were normal. Methods. Thirty-two patients (21 women and 11 men; age range, 20-87 years) with a known primary malignancy were enrolled in the study. The patients were evaluated with conventional sonography, unenhanced PIHI, and PIHI 3 minutes after the injection of Levovist (SH U 508A; Schering AG, Berlin, Germany). All patients also underwent triphasic helical CT within 1 week after sonography. In 1 patient, mangafodipir-enhanced magnetic resonance imaging was performed as part of the clinical workup. Results. After Levovist injection, in 4 (12.5%) of 32 patients, at least 1 hypoechoic lesion was detected by PIHI; multiple lesions were shown in 1 patient. The mean diameter of newly detected lesions was 12 mm. Triphasic helical CT also showed all of the lesions that were detected by PIHI. The diagnoses were confirmed by biopsy and CT findings in 2 patients and by the typical CT and magnetic resonance imaging findings in 1 patient. For the fourth patient, the diagnosis was confirmed by fol-low-up and CT Conclusions. Late-phase PIHI is comparable to helical CT for detecting occult hepatic metastases, but it protects patients from the potentially hazardous effects of radiation and iodinated contrast agents. Further series involving a larger number of patients are needed to determine its place in the evaluation of cancer staging and treatment planning. |
| Databáze: | OpenAIRE |
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