Recent advances in understanding the hepatotoxicity associated with protein kinase inhibitors
| Autor: | Qiang Shi, Lijun Ren, William B. Mattes, Xi Yang |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Pharmacology
Kinase Chemistry General Medicine Mitochondrion Toxicology 030226 pharmacology & pharmacy Small molecule Food and drug administration 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Liver 030220 oncology & carcinogenesis Regorafenib Hepatocytes Animals Humans Chemical and Drug Induced Liver Injury Protein kinase A Protein Kinase Inhibitors health care economics and organizations |
| Zdroj: | Expert opinion on drug metabolismtoxicology. 16(3) |
| ISSN: | 1744-7607 |
| Popis: | Introduction: As of October 2019, the U.S. Food and Drug Administration (FDA) has approved 53 small molecule kinase inhibitors (KI), which account for about 10% of all FDA-approved new molecular en... |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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