Acute jaundice in Vientiane, Lao People's Democratic Republic
| Autor: | Keiji Matsubayashi, Christi Scheffel, Maidy Pranata Putri, Mark Hayden, Sithat Insisiengmay, Susanna Widjaja, Boonyos Raengsakulrach, Andrew L. Corwin, Kazushige Iinuma, David W. Vaughn, Kanti Laras, Khanthong Bounlu, Khemphet Vanthanouvong, Kenneth C. Hyams, Timothy P. Endy, Saykham |
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| Rok vydání: | 1998 |
| Předmět: |
Microbiology (medical)
Adult Male medicine.medical_specialty Adolescent Hepatitis Viral Human Hepatitis C virus Jaundice medicine.disease_cause Hepatitis E virus Risk Factors Internal medicine medicine Humans Hepatitis Antibodies Child Aged Hepatitis biology business.industry Hepatitis A medicine.disease biology.organism_classification GB virus C Leptospirosis Infectious Diseases Laos Case-Control Studies Child Preschool Immunology Acute Disease Female medicine.symptom business Viral hepatitis |
| Zdroj: | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 27(4) |
| ISSN: | 1058-4838 |
| Popis: | Analysis of serum samples from patients with acute jaundice by means of enzyme-linked immunosorbent assay and polymerase chain reaction testing provided the first profile of this condition in Vientiane, Lao PDR, in 1995 and 1996. In a case-control, hospital-based study, evidence of acute infections due to hepatitis A and B viruses was found in 14% and 10% of cases, respectively. Hepatitis E virus, however, did not appear to contribute to clinically recognized acute jaundice. Similarly, antibody to hepatitis C virus was recognized in almost equal proportions of cases (8%) and controls (6%), thus representing probable background infections. The detection of hepatitis G virus marks the first report of this virus in Lao PDR. The large proportion (21%) of new leptospiral infections in cases without acute hepatitis A or B was notable. This finding suggests significant regional underreporting of leptospirosis as a cause of acute jaundice. The limited laboratory diagnostic capabilities for confirming a differential diagnosis of leptospirosis contribute to the lack of attention paid to this important health problem. |
| Databáze: | OpenAIRE |
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