Assessment of drinking water fortification with iron plus ascorbic acid or ascorbic acid alone in daycare centers as a strategy to control iron-deficiency anemia and iron deficiency: a randomized blind clinical study
| Autor: | Carlos Alberto Nogueira de Almeida, Carolina Regina João, Elza Daniel de Mello, Adriana P R Ramos, Camila Aparecida João, J E Dutra-de-Oliveira |
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| Rok vydání: | 2014 |
| Předmět: |
Male
medicine.medical_specialty Anemia Iron Fortification Nutritional Status Ascorbic Acid Gastroenterology EDUCAÇÃO EM SAÚDE Hemoglobins Double-Blind Method Internal medicine Prevalence medicine Humans Mean corpuscular volume Anemia Iron-Deficiency biology medicine.diagnostic_test business.industry Drinking Water Child Day Care Centers Iron Deficiencies Vitamins Iron deficiency medicine.disease Ascorbic acid Ferritin Nutrition Assessment Treatment Outcome Infectious Diseases Biochemistry Iron-deficiency anemia Child Preschool Food Fortified Pediatrics Perinatology and Child Health biology.protein Female Hemoglobin business Brazil circulatory and respiratory physiology |
| Zdroj: | Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Universidade de São Paulo (USP) instacron:USP |
| Popis: | Objective Assess drinking water fortification with iron and/or ascorbic acid as a strategy to control iron-deficiency anemia and iron deficiency. Methods Randomized blind clinical study, fortifying drinking water to 153 pre-school children during 3 months, with iron and ascorbic acid (A), ascorbic acid (B) or plain water (C). Hemoglobin (Hb), mean corpuscular volume (MCV) and ferritin were measured. Results Within the groups, Hb raised in all three groups, MCV in A and B and ferritin in A. The difference between time points 0 and 1 was significant between A and B for Hb, when A and B were compared with C for MCV and when A was compared with either B or C for ferritin. Conclusions Water fortification is efficient in controlling iron deficiency and anemia. Iron stores' recovery depends on a more effective offer of iron. Water fortification must be preceded by a careful assessment of the previous nutritional status. |
| Databáze: | OpenAIRE |
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