Functioning of patients with chronic idiopathic axonal polyneuropathy (CIAP)
Autor: | Paul J. M. Helders, Nico L. U. van Meeteren, Nicolette C. Notermans, Peter G. Erdmann, Frank R. van Genderen, Eline Lindeman, L. L. Teunissen |
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Rok vydání: | 2007 |
Předmět: |
Male
chronic idiopathic axonal polyneuropathy medicine.medical_specialty Neurology Cross-sectional study Clinical Neurology Diagnostic Techniques Neurological Comorbidity Walking Axonal polyneuropathy functioning Polyneuropathies Physical medicine and rehabilitation International Classification of Functioning Disability and Health medicine Humans In patient Fatigue Aged Netherlands Original Communication Muscle Weakness business.industry Muscle weakness medicine.disease Axons CIAP Motor Skills Disorders Cross-Sectional Studies Chronic Disease Physical therapy Female Neurology (clinical) medicine.symptom business Polyneuropathy Muscle Contraction |
Zdroj: | Journal of Neurology |
ISSN: | 1432-1459 0340-5354 |
DOI: | 10.1007/s00415-006-0501-8 |
Popis: | Although patients with Chronic Idiopathic Axonal Polyneuropathy (CIAP) report a slow deterioration of sensory and motor functions, the impact of this deterioration on daily functioning has not yet been investigated in detail. The first aim of this crosssectional study involving 56 patients with CIAP was, therefore, to assess patients’ functioning with use of the International Classification of Functioning, Disability and Health (ICF). The second aim was to find determinants of walking ability, dexterity, and autonomy. Fatigue and limited walking ability were present in most patients and differed considerably. In regression models, age, muscle strength, and fatigue together explained 63% of the variance in walking ability, which by itself explained almost 50% of the variance in patients’ autonomy indoors and outdoors (42% and 49%, respectively). Muscle strength and sensory function scores together explained 30% of the variance in dexterity scores, which in turn explained only 13% of the variance in autonomy indoors. The diminished autonomy of patients with CIAP might be improved by reducing fatigue, by means of training, and by improving walking ability. |
Databáze: | OpenAIRE |
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