A novel simian retrovirus subtype discovered in cynomolgus monkeys (Macaca fascicularis)
| Autor: | Anthony Cooke, Rong Rong, Changjun Shi, Ron Berger, Chen Xie, Lingyan Yang, Si Chen, Lisa Tomanek, Chih-Ling Zao |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
040301 veterinary sciences Histopathological examination Genome Virus Serology 0403 veterinary science 03 medical and health sciences Open Reading Frames Viral Proteins Simian retrovirus Phylogenetics Virology Animals Phylogeny biology Phylogenetic tree Monkey Diseases 04 agricultural and veterinary sciences biology.organism_classification Retroviruses Simian Open reading frame Macaca fascicularis 030104 developmental biology Retroviridae Infections |
| Zdroj: | The Journal of general virology. 97(11) |
| ISSN: | 1465-2099 |
| Popis: | A new simian retrovirus (SRV) subtype was discovered in China and the USA from Cambodian-origin cynomolgus monkeys. Histopathological examination from necropsied animals showed multifocal lymphoplasmacystic and histocytic inflammation. The complete genome sequences demonstrated that the US virus isolates were nearly identical (99.91–99.93 %) and differed only slightly (99.13–99.16 % identical) from the China isolate. Phylogenetic analysis showed that the new virus isolates formed a distinct branch of SRV-1 through -7, and therefore were named this subtype, SRV-8. This SRV-8 variant was also phylogenetically and serologically more closely related to SRV-4 than any other SRV subtype. |
| Databáze: | OpenAIRE |
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