Physiologically Based Modeling to Predict Monoclonal Antibody Pharmacokinetics in Humans from in vitro Physiochemical Properties

Autor:	David D'Argenio, Amita Datta-Mannan, Shihao Hu
Rok vydání:	2022
Předmět:	Kinetics Heparin Immunology Antibodies Monoclonal Humans Immunology and Allergy Tissue Distribution Models Biological
Zdroj:	mAbs. 14
ISSN:	1942-0870 1942-0862
Popis:	A model-based framework is presented to predict monoclonal antibody (mAb) pharmacokinetics (PK) in humans based on
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0b9f0b8b245d2cd0f364dea815816ad https://doi.org/10.1080/19420862.2022.2056944 Zobrazit plný text záznamu