Epidemiological survey on the relationship between different iodine intakes and the prevalence of hyperthyroidism

Autor: Fan Yang, Bingyuan Cui, Zhan-yi Wang, Haixia Guan, Wei Chen, Yushu Li, Bai Yuan, Fengnan Hu, Ya-jie Tong, Xiaoguang Shi, Weiping Teng, Ying Jin, Shi-ming Yang, Zhongyan Shan
Rok vydání: 2002
Předmět:
Zdroj: European journal of endocrinology. 146(5)
ISSN: 0804-4643
Popis: OBJECTIVE: To investigate the effect of different levels of iodine intake on the prevalence of hyperthyroidism and the impact of universal salt iodization on the incidence of hyperthyroidism. DESIGN: A comparative cross-sectional and longitudinal survey was conducted in three areas with borderline iodine deficiency, mild iodine excess (previously mild iodine deficiency) and severe iodine excess. Universal salt iodization had been introduced 3 years previously except in the area with borderline iodine deficiency. METHODS: In total 16 287 inhabitants from three areas answered a questionnaire concerning the history of thyroid disease. Among them 3761 unselected subjects received further investigations including thyroid function, thyroid autoantibodies, thyroid ultrasonography and urinary iodine excretion. RESULTS: Among areas with median urinary iodine excretion of 103 microg/l, 375 microg/l and 615 microg/l (P
Databáze: OpenAIRE