The occurrence of IgA pemphigus foliaceus without neutrophilic infiltration
| Autor: | E. Neumann, Marian Dmochowski, M. Raptis, Monika Bowszyc-Dmochowska, J. Bowszyc |
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| Rok vydání: | 1994 |
| Předmět: |
Pathology
medicine.medical_specialty integumentary system Epidermis (botany) medicine.diagnostic_test biology Neutrophils Dermatology medicine.disease Immunofluorescence Immunoglobulin A medicine.anatomical_structure Dermis Immunopathology Immunology medicine biology.protein Humans Female IgA pemphigus Stratum spinosum Antibody Pemphigus Pemphigus foliaceus Aged |
| Zdroj: | Clinical and Experimental Dermatology. 19:56-58 |
| ISSN: | 1365-2230 0307-6938 |
| DOI: | 10.1111/j.1365-2230.1994.tb01117.x |
| Popis: | Summary A 70-year-old woman with pemphigus foliaceus is reported. Direct immunofluoscence performed on perilesional skin revealed deposits of IgA, C3 and lambda chains in the intercellular substance of the upper stratum spinosum. indirect immunofluorescence demonstrated serum antibodies of the IgA class against the intercellular region of the upper epidermis at an initial titre of 1:2560. Histological studies, performed together with immunofluorescence revealed an absence of a district neutrophil infiltrate either in the epidermis or dermis, contrary to the findings in cases with intra-epidermal IgA deposits reported previously. |
| Databáze: | OpenAIRE |
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