Erythropoietin Levels in Heterozygous Alpha-Thalassemia

Autor:	M, Vedovato, G, Salvatorelli, G C, Balboni, M, Taddei Masieri, B, Dolcini, C, Toffoli
Rok vydání:	1986
Předmět:	Adult Male Heterozygote Adolescent Humans Thalassemia Female Hematology General Medicine Middle Aged Child Erythropoietin
Zdroj:	Acta Haematologica. 76:159-160
ISSN:	1421-9662 0001-5792
DOI:	10.1159/000206042
Popis:	In guinea pig bone marrow cultures with heterozygous alpha-thalassemic serum, 59Fe uptake values are elevated above iron values of cultures with serum of normal subjects. These results show that erythropoietin (EP) activity values in heterozygous alpha-thalassemia are comparable to those previously observed by ourselves in heterozygous beta-thalassemia despite of the different Hb concentration in these thalassemic syndromes. This points to the existence of signals which regulate Ep synthesis independently of Hb levels.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0a8d06070238a04eb1ecaadc8f5b4df https://doi.org/10.1159/000206042 Zobrazit plný text záznamu