Regioselective lithiation of benzyl imidazole: Synthesis and evaluation of new organocatalysts for trans-diol functionalization

Autor:	Mohamed F. El-Mansy, Paul Ha-Yeon Cheong, Rich G. Carter, Ankan Ghosh
Rok vydání:	2019
Předmět:	chemistry.chemical_compound Benzimidazole chemistry Deuterium Organocatalysis Organic Chemistry Diol Imidazole Organic chemistry Regioselectivity Surface modification Chemical reaction
DOI:	10.6084/m9.figshare.9751994.v1
Popis:	Benzyl imidazole was successfully lithiated using n-BuLi at −78 °C and verified by deuterium incorporation. The chemical reaction of the lithiated benzimidazole was explored with a series of different electrophiles. This approach was utilized to synthesize new anti and syn diphenyl organocatalysts for trans-diol functionalization.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0a89b5cd6d49c9ce17c2d46396e91b9 Zobrazit plný text záznamu