The state of the digestive system in children with systemic connective tissue diseases
| Autor: | I. D. Chyzhevskaya, L. M. Belyaeva |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
biology business.industry Nausea Stomach Connective tissue Arthritis Heartburn Helicobacter pylori biology.organism_classification medicine.disease Pediatrics Gastroenterology RJ1-570 children systemic connective tissue diseases juvenile idiopathic arthritis juvenile scleroderma systemic lupus erythematosus digestive organs medicine.anatomical_structure Internal medicine Pediatrics Perinatology and Child Health medicine Esophagus medicine.symptom business Pathological |
| Zdroj: | Rossijskij Vestnik Perinatologii i Pediatrii, Vol 65, Iss 1, Pp 65-70 (2020) |
| ISSN: | 2500-2228 1027-4065 |
| Popis: | Purpose. To study the prevalence of the digestive system pathology in children with systemic connective tissue diseases.Characteristics of children and research methods. We carried out a clinical and instrumental examination of 108 children with systemic connective tissue diseases hospitalized in the rheumatology department of the 4th City Children’s Clinical Hospital in Minsk from 2008 to 2015. 60 patients suffered from juvenile idiopathic arthritis (mean age 12.3 [9.4; 15.6] years), 23 children suffered from juvenile scleroderma (mean age 11.8 [9.7; 14.9] years) and 25 children suffered from systemic lupus erythematosus (mean age 13.1 [12.2; 16.3] years). All patients received long-term immunosuppressive and anti-inflammatory therapy.Results. 75.9% patients had gastroenterological complaints, such as abdominal pains, nausea, heartburn. 69.4% of patients had endoscopic changes in the esophagus, stomach, and/or duodenum. According to the results of the morphological study, 43.5% of patients with systemic connective tissue diseases had mild inflammatory process, 29.6% of patients had average inflammatory process, and 3.7% of patients had severe inflammatory process. Among the children examined, 33 (55%) patients with juvenile idiopathic arthritis, 12 (48%) children with systemic lupus erythematosus and 11 (47.8%) patients with juvenile scleroderma were infected with Helicobacter pylori. Pathological changes of the hepatobiliary system and pancreas were diagnosed in 83.3% of children with systemic connective tissue diseases.Conclusion. The revealed changes indicate a probable connection between the pathology of the digestive organs in children with systemic connective tissue diseases and substantiate the gastroenterological examination of this category of patients. |
| Databáze: | OpenAIRE |
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