A comparative multicentre study evaluating gluteal turnover flap for wound closure after abdominoperineal resection for rectal cancer
| Autor: | Gijsbert D. Musters, Pieter J. Tanis, Oren Lapid, A. A. W. van Geloven, Baljit Singh, Sanjay Chaudhri, S. Sparenberg, J. J. W. van Dam, Sarah Sharabiany, Roel Hompes, F. Runau, Robin D. Blok, A. W. H. van de Ven |
|---|---|
| Přispěvatelé: | Graduate School, Center of Experimental and Molecular Medicine, CCA - Imaging and biomarkers, CCA - Cancer Treatment and Quality of Life, Amsterdam Gastroenterology Endocrinology Metabolism, Plastic, Reconstructive and Hand Surgery, ACS - Diabetes & metabolism, Amsterdam Movement Sciences, Surgery |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Colorectal cancer Perineum Wound closure Surgical Flaps 03 medical and health sciences Postoperative Complications 0302 clinical medicine Clinical endpoint Abdominoperineal resection Humans Medicine Rectal cancer Perineal hernia Retrospective Studies Proctectomy Rectal Neoplasms business.industry Gastroenterology medicine.disease University hospital Colorectal surgery Surgery 030220 oncology & carcinogenesis Original Article 030211 gastroenterology & hepatology Perineal wound healing Neoplasm Recurrence Local business Abdominal surgery |
| Zdroj: | Techniques in coloproctology, 25(10), 1123-1132. Springer-Verlag Italia Techniques in Coloproctology |
| ISSN: | 1123-6337 |
| Popis: | Background The aim of this study was to compare perineal wound healing between gluteal turnover flap and primary closure in patients undergoing abdominoperineal resection (APR) for rectal cancer. Methods Patients who underwent APR for primary or recurrent rectal cancer with gluteal turnover flap in two university hospitals (2016–2021) were compared to a multicentre cohort of primary closure (2000–2017). The primary endpoint was uncomplicated perineal wound healing within 30 days. Secondary endpoints were long-term wound healing, related re-interventions, and perineal herniation. The perineal hernia rate was assessed using Kaplan Meier analysis. Results Twenty–five patients had a gluteal turnover flap and 194 had primary closure. The uncomplicated perineal wound-healing rate within 30 days was 68% (17/25) after gluteal turnover flap versus 64% (124/194) after primary closure, OR 2.246; 95% CI 0.734–6.876; p = 0.156 in multivariable analysis. No major wound complications requiring surgical re-intervention occurred after flap closure. Eighteen patients with gluteal turnover flap completed 12-month follow-up, and none of them had chronic perineal sinus, compared to 6% (11/173) after primary closure (p = 0.604). The symptomatic 18-month perineal hernia rate after flap closure was 0%, compared to 9% after primary closure (p = 0.184). Conclusions The uncomplicated perineal wound-healing rate after the gluteal turnover flap and primary closure after APR is similar, and no chronic perineal sinus or perineal hernia occurred after flap closure. Future studies have to confirm potential benefits of the gluteal turnover flap. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink